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基础医学系

闫利明

履历

    2016- 至今    清华大学  医学院  助理研究员

    2013 – 2016   清华大学  医学院  博士后

    2009 – 2013   清华大学  医学院  博士

    2006 – 2009   福建农林大学  微生物专业  硕士

    2002 – 2006   安徽科技学院  生物技术专业  学士


研究领域与方向

动力类蛋白介导膜的形变和拓扑重构,阐明细胞膜动态变化的分子机制;管状内质网的同源融合、线粒体的融合与分裂以及内质网与质膜的相互作用。

学术荣誉与奖励

关键词

代表性论文

1. Liming Yan*, Yuanbo Qi*, Xiaofang Huang*, Caiting Yu*, Lan Lan, Xiangyang Guo, Zihe Rao, Junjie Hu, Zhiyong Lou. Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating mitochondrial fusion, Nature Structural Molecular Biology, 2018, 25(3): 233-243.

2. Yuanbo Qi*, Liming Yan*, Caiting Yu*, Xiangyang Guo, Xin Zhou, Xiaoyu Hu, Xiaofang Huang, Zihe Rao, Zhiyong Lou, and Junjie Hu. Structures of human Mitofusin 1 provide insight into mitochondrial tethering. Journal of Cell Biology. 2016, 215(5): 621-629.

3. Yao R*, Ming Z*, Yan L*, Li S*, Wang F, Ma S, Yu C, Yang M, Chen L, Chen L, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Z, Lou Z, Xie D. DWARF14 is a non-canonical hormone receptor for strigolactone. Nature. 2016 Aug 25; 536(7617): 469-73.

4. Yan LM*, Sun S*, Wang W, Shi JM, Hu XY, Wang SY, Su D, Rao ZH, Hu JJ, Lou ZY.Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion. Journal of Cell Biology. 2015 Sep 14;210(6):961-72.

5. Yan L*, Ma Y*, Liu D*, Wei X, Sun Y, Chen X, Zhao H, Zhou J, Wang Z, Shui W, Lou Z.Structural basis for the impact of phosphorylation on the activation of plant receptor-like kinase BAK1.Cell Research. 2012 Aug; 22(8): 1304-8.

6. Yan L*, Ma Y*, Sun Y, Gao J, Chen X, Liu J, Wang C, Rao Z, Lou Z.Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission. J Mol Cell Biol. 2011 Dec; 3(6): 378-81.


联系方式

Email: yanlm at xtal.tsinghua.edu.cn

Phone: 86-10-62772291

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