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基础医学系

裘莹

履历

    2013.12-至今 清华大学,医学院,教学中心,副教授

    2011.3-2013.11清华大学,医学院,教学中心,讲师

    01/2010-2/2011同济大学,医学院,病理教研室,副教授

    09/2002-12/2009同济大学,医学院,病理教研室,讲师

    03/2004- 12/2009日本大阪大学,医学院,病理学, Ph.D.

    09/1991-07/2002同济大学,医学院,临床医学,M.D.

研究领域与方向

作为一名教师,教书育人是我们的天职。离开教学的教师不是真正意义上的教师。但大学的教师又与中学的不同,我们是需要科研研究来丰富我们的教学理念和更新我们的知识结构,在传授知识的同时也在不断推动我们自身知识领域的不断进步,同时也在身体力行的教给学生如何建立他们个性化的学习模式,这就是我对大学教师教学的理解。学生既像是我们的孩子又像是我们的亲密朋友。我们在传授知识给学生的同时又在不断的从他们新生力量中获得能量和产生新的奇妙的想法。互相学习、互相感染,共同进步。

学术荣誉与奖励

关键词

癌基因, 肿瘤转移, 预后

代表性论文

1. Fangli Ren, Yongtao Geng, Takayuki Minami1, Ying Qiu, Yarui Feng, Chunxiao Liu, Juan Zhao, Yinyin Wang, Xuanzi Fan, Yangmeng Wang, Mengdi Li, Jun Li*, and Zhijie Chang*. Nuclear termination of STAT3 signaling through the SIPAR (STAT3-Interacting Protein As a Repressor) adaptor recruiting T cell tyrosine phosphatase TC-PTP. FEBS Letters. Jul 8;589(15):1890-6 2015.

2. Wang Yangmeng, Ren Fangli, Wang Yinyin, Feng Yarui, Wang Dianjun, Jia Baoqing, Qiu Ying, Wang Shiyan, Yu Jun, Sung Joseph JY, Xu Jiake, Zeps Nikolajs, Chang Zhijie. CHIP/Stub1 functions as a tumor suppressor and represses NF-kB-mediated signaling in colorectal cancer. Carcinogenesis. 2014, May; 35 (5):983-91.

3. Hongxiu Ning, Fangli Ren, Yuanjiang Zhang, Yu Rong, Yinyin Wang, Fuqin Su, Chenguang Cai, Zhe Jin, Zhiyong Li, Xinqi Gong, Yonggong Zhai, Dianjun Wang, Baoqing Jia, Ying Qiu, Xinyuan Fu, Y. Eugene Chin, and Zhijie Chang. Stabilizes the TC45/STAT3 Association and Promotes Dephosphorylation of STAT3 to Repress Tumorigenesis. Mol Cell. 53:752-765, 2014

4. Yongtao Geng, Yanfang Ju, Fangli Ren, Ying Qiu, Yasuhiko Tomita, Miki Tomoeda, Mioka Kishida, Yinyin Wang, Lian Jin, Fuqin Su, Chunhong Wei, Baoqing Jia, Yi Li1*, Zhijie Chang*. Insulin Receptor Substrate 1/2 (IRS1/2) Regulates Wnt/β-catenin Signaling through Blocking Autophagic Degradation of Dishevelled2. J. Biol. Chem. 289(16), 11230–11241, 2014.

5. 金淑清,浦予飞,裘莹*,青笹克之,森井英一. ELF2表达水平与非小细胞肺癌患者预后相关性分析. 浙江大学学报(医学版)2014, 43(4): 413-419. 

6. Ying QIU, Zhu-ling WANG, Shu-qing JIN, Yu-fei PU, Satoru TOYOSAWA, Katsuyuki AOZASA. Eiichi MORIIE. Expression level of Pre B Cell leukemia transcription factor 2 (PBX2) as a prognostic marker for gingival squamous cell carcinoma. J Zhejiang Univ-Sci B (Biomed & Biotechnol). 2012,13(3): 168-175.

7. 刘娟, 裘莹, 何晶, 文蕾, 管晓菲, 袁琼兰. 人参皂苷Rb1和Rg1对海马神经元的影响. 同济大学学报(医学版). 2011 (3): 1-6. 

8. 金淑清,浦予飞,裘莹.HOX基因的研究进展.癌症进展.2010 (2): 154-158.

9. Mamat S, Ikeda J, Enomoto T, Ueda Y, Rahadiani N, Tian T, Wang Y, Qiu Y, Kimura T, Aozasa K, Morii E. Prognostic significance of CUB domain containing protein expression in endometrioid adenocarcinoma. Oncology Rep. 2010, 23(5): 1221-1227. 

10. Nur Rahadiani, Jun-ichiro Ikeda, Tomoki Makino, Tian Tian, Ying Qiu, Suhana Mamat, Wang Yi, Yuichiro Doki, Katsuyuki Aozasa, Eiichi Morii. Tumorigenic role of podoplanin in esophageal squamous cell carcinoma. Annals of Surgical Oncology. 2010,17(5):1311-23.

11. Ying Q, Bogen S, Guifen Z, Biyong D, Tomoki M, Yasuhiko T, Junchen W, Wenjuan L, Yuichiro D, Katsuyuki A, Eiichi M. Expression level of Pre B cell leukemia homeobox 2(PBX2) correlates with poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma. Int J Oncology. 2010, 36: 651-663.

12. Oda T, Tian T, Ikeda JI, Ying Q, meinosin, Katsuyuki A, Eiichi M. Tumorigenic role of orphan nuclear receptor NR0B1 in lung adenocarcinoma. Am J of Pathol. 2009,175: 1235-1245.

13. Ying Q, Eiichi Morii, Yasuhiko Tomita, Binglin Zhang, Akihide Matsumura, Masanori Kitaichi, Meinoshin Okumura, Katsuyuki Aozasa. Prognostic significance of pre B cell leukemia transcription factor 2(PBX2) expression in non-small cell lung carcinoma. Cancer Science. 2009, 100: 1198-209.

14. Zhang B, Tomita Y, Ch'ng E, Qiu Y, He J, Jin YF, Tomoeda M, Hamada K, Ueda T, Aozasa K. Prognostic significance of phosphorylated FOXO1 expression in soft tissue sarcoma Ann. Surg. Oncol. 2009; 16:1925-37.

15. Hamada K, Tomita Y, Qiu Y, Tomoeda M, Ueda T, Tamai N, Hashimoto N, Yoshikawa H, Aozasa K, Hatazawa J. 18F-FDG PET analysis of schwannoma: increase of SUVmax in the delayed scan is correlated with elevated VEGF/VPF expression in the tumors. Skeletal Radiol. 2009; 38:261-266.

16. Naoto Nakamichi, Eiichi Morii, Jun-ichiro Ikeda, Ying Qiu, Suhana Mamato, Tian Tian, Shirou Fukuhara, and Katsuyuki Aozasa. Synergistic effect of interleukin 6 and endoplasmic reticulum stress inducers on the high level of ABCG2 expression in plasma cells. Laboratory Investigation. 2009; 89, 327–336.

17. Ying Qiu, Eiichi Morii, Binglin Zhang, Yasuhiko Tomita, Katsuyuki Aozasa. E74-like factor 2 transactivates valosin-containing protein gene, a gene involved in cancer growth. Exp Mol Pathol. 2008, 84: 226-229.

18. Ikeda JI, Morii E, Liu Y, Qiu Y, Nakamichi N, Jokoji R, Miyoshi Y, Noguchi S, Aozasa K. Prognostic significance of CD55 expression in breast cancer. Clin Cancer Res. 2008, 14:4780-4786.

19. Hamada K, Tomita Y, Qiu Y, Zhang B, Ueda T, Myoui A, Higuchi I, Yoshikawa H, Aozasa K, Hatazawa J. 18F-FDG-PET of musculoskeletal tumors: a correlation with the expression of glucose transporter 1 and hexokinase II. Ann Nucl Med. 2008; 22:699-705.

20. Ying Qiu, Yasuhiko Tomita, Binglin Zhang, Itsuko Nakamichi, Eiichi Morii, Katsuyuki Aozasa. Pre-B-cell leukemia transcription factor 1 regulates expression of Valosin-containing protein, a gene involed in cancer growth. Am J of Pathol. 2007, 170: 152-159.

21. Binglin Z, Yasuhiko T, Ying Q, Katsuyuki A. E74-like factor 2 regulates valosin-containing proteins expression. BBRC. 2007, 356: 536-541.

22. weseng C, Yasuhiko T, Binglin Z, Juxiang H, Yoshihiko H, Ying Q, Morii E, Nakamichi I, Hamada K, Ueda T, Aozasa K. Prognostic significance of CD100 expression in soft tissue sarcoma. American Cancer Society. 2007, 22:164-172.

23. Tomita Y, Morooka T, Hoshida Y, Zhang B, Qiu Y, Nakamichi I, Hamada K, Ueda T, Naka N, Kudawara I, Aozasa K. Prognostic significance of activated AKT expression in soft-tissue sarcoma. Clin Cancer Res. 2006, 12:3070-3077.

24. Yasuhiko T, Takaya M, Yoshihiko H, Binglin Z, Ying Q, Nakamichi I, Hamada K, Ueda T, Naka N, Kudawara I, Aozasa K. Ressessment of the 1993 Osaka grading system for localized soft tissue sarcoma in Japan. Anticancer Reseach. 2006, 26:4665-4669.

25. Qiu Y, Song BG, Wang JC. Expression Level of Valosin-Containing Protein Is Associated With Prognosis of Gastric Carcinoma. Chinese journal of Cancer.2006, 26:935-940.

26. Yamamoto S, Tomita Y, Hoshida Y, Uruno T, Qiu Y, Iizuka N, Monden M, Miyauchi A, Aozasa K. Expression of Valosin Containing Protein(p97) is Associated with disease recurrence in Follicular Thyroid Cancer. Ann Surg Oncol.2005; 12: 925-934.

27. Ying Q, Yongyu L, Shuguang L, Bogen S, Guifen Z. Effect of Qingyitang on activity of intracellular Ca2+-Mg2+-ATPase in rats with acute pancreatitis. World Journal of Gastroenterology. 2004; 10:100-104.

28. Qiu Y, Li YY, Li SG, et al. Effect of Qingyi decoction on Ca2+-Mg2+-ATPase in pancreatic and liver cells of rats with acute pancreatitis. Chinese journal of integrated traditional and western medicine.2003; 23:112-115.

29. Qiu Y, Li SG, Li YU. The variation of intracellular Ca2+-Mg2+-ATPase activity in acute pancreatitis rats and the effect of Vit E. Journal of Tongji University.2002; 23:276-281.

30. Qiu Y, Li YY. Reach mechanism of cellular calcium overload in acute pancreatitis(the change of intracellular calcium-magnesium ATPase(Ca2+-Mg2+-ATPase) activity. Foreign medical sciences(section of digestive disease). 2002; 22:115-118.

31. Qiu Y, Song BG, Shen LX, Zhao GF. A correlation study between bcl-2 protein expression and gastric cancer. Journal of Tongji University. 2001; 22:15-17.

32. Song BP, Qiu Y, Li YM. Expression of oncoprotein in pituitary adenomas. Shanghai Tiedao Daxue Xuebao.2001; 21:5-7.


联系方式

Email: yingqiu at biomed.tsinghua.edu.cn

Phone: +86-10-62796747

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