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生物医学工程系

黄国亮

履历

    2004- 至今 清华大学 医学院生物医学工程系

    1999-2003 清华大学 生物系

    1995-1999 清华大学 精仪系

    1991-1995 清华大学 精仪系 博士

    1984-1991 北京师范大学 物理系 本科和硕士


研究领域与方向

从事生物医学检测技术创新研究与新型科学仪器、医疗仪器的开发工作,包括生物芯片检测技术、多模态分子影像技术、痕量样品光纤传感技术、高光谱白光干涉超分辨成像技术、眼象健康无影成像技术、微流控芯片核酸分析分子诊断技术等。其中微流控芯片核酸多指标分子诊断技术与系统,是健康中国低成本精准医疗的平台技术,获得国家创新医疗器械产品批准、Ⅲ类医疗器械产品注册证和CE认证,教育部组织专家技术鉴定为国际领先水平,在生命科学与医学科研、临床医疗、食品安全、卫生防疫、家庭健康监护等具有广泛应用前景。


学术荣誉与奖励

关键词

biosensor, in-vivo imaging, micro-nano biomedical analysis, molecular diagnostics, visualization of living cell function

代表性论文

1. Qi Li,Rongxin Fu,Junqi Zhang, Ruliang Wang, Jiancheng Ye, Ning Xue, Xue Lin, Ya Su, Wupeng Gan, Ying Lu, and Guoliang Huang(通讯作者), A label-free method using weighted-phase algorithm to quantitate nanoscale interactions between molecules on DNA microarray, Analytical Chemistry, 2017, DOI:10.1021/acs. analchem.6b04596.(SCI IF 5.886)

2. Junqi Zhang, Rongxin Fu, Liping Xie, Qi Li, Wenhan Zhou, Ruliang Wang, Jiancheng Ye, Dong Wang, Ning Xue, Xue Lin, Ying Lu and Guoliang Huang(通讯作者),A smart device for label-free and real-time detection of gene point mutations based on the high dark phase contrast of vapor condensation,Lab on a Chip, V15, p3891–3896, 2015。(SCI IF 6.115)

3. Guoliang Huang(通讯作者), Qin Huang, Li Ma, Xianbo Luo, Biao Pang, Zhixin Zhang, Ruliang Wang, Junqi Zhang, Qi Li, Rongxin Fu, and Jiancheng Ye,fM to aM nucleic acid amplification for molecular diagnostics in a non-stick-coated metal microfluidic bioreactor,Scientific Reports, V4(7344),p1-9, 2014。(SCI, IF5.578)

4. Tongzhou Wang, Qiang Li, Xin Li, Songmin Zhao, Ying Lu and Guoliang Huang (通讯作者),Use of hyperspectral imaging for label-free decoding and detection of biomarkers,Optics Letters,V38, p1524-26, 2013。(SCI, IF3.4)

5. Xin Li, Zhuoqi Li, Wupeng Gan,Tongzhou Wang, Songmin Zhao,Ying Lu, Jing Cheng and Guoliang Huang(通讯作者), Sensitive and High Resolution Subcutaneous Fluorescence in vivo Imaging Using Upconversion Nanoparticles and Microarray,Analyst,V138, p3711-3718,2013. (SCI, IF4.2)

6.Qiang Li, Kaihuan Zhang, Tongzhou Wang, Xinying Zhou, Jia Wang, Chen Wang, Haixiao Lin,Xin Li, Ying Lu and Guoliang Huang (通讯作者),Color-encoded microcarriers based on nano-silicon dioxide film for multiplexed immunoassays,Analyst, V137, p3760–3766, 2012。(SCI, IF4.2)

7.Xin Li, Qiang Li, Hong Zhou, Hongxia Hao, Tongzhou Wang, Songmin Zhao, Ying Lu, Guoliang Huang (通讯作者),Rapid, On-Site Identification of Explosives in Nanoliter Droplets Using a UV Reflected Fiber Optic Sensor,Analytica Chimica Acta,V751, p112– 118, 2012。(SCI, IF4.5)

8.Qiang Li, Tian Qiu, Hongxia Hao, Hong Zhou,Tongzhou Wang, Ye Zhang, Xin Li, Shengyi Chen, Guoliang Huang (通讯作者)and Jing Cheng, Rapid On-site Analysis of Illegal Drugs in Nano-microscale by a Deep Ultraviolet-visible Reflected Optical Fiber Biosensor, Analyst, V137 (7), p1596-1603, 2012。(SCI, IF4.2)

9.Shengyi Chen, Tao Deng, Tongzhou Wang, Jia Wang, Xin Li, Qiang Li and Guoliang Huang(通讯作者), Visualization of high-throughput and label-free antibody-polypeptide binding for drug screening based on microarrays and surface plasmon resonance imaging, Journal of Biomedical Optics, V17(1), p015005(1-8) , 2012。(SCI, IF3.2)

10. Guoliang Huang(通讯作者), Can Wang, Li Ma, Xu Yang, Xiaoyong Yang, Guoqing Wang, Sensitive sequence-specific molecular identification system comprising an aluminum micro-nanofluidic chip and associated real-time confocal detector, Analytica Chimica Acta, V695, 1-10, 2011。(SCI, IF4.3)

11. Rui Ma, Lan Xie, Chao Han, Kai Su, Tian Qiu, Lei Wang, Guoliang Huang, Wanli Xing, Jie Qiao, Jundong Wang and Jing Cheng,In Vitro Fertilization on a Si ngle-Oocyte Positioning System Integrated with Motile Sperm Selection and Early Embryo Development, Analytical Chemistry, V83, 2964-2970, 2011。(SCI, IF5.2)

12.Lan Xie, Rui Ma, Chao Han, Kai Su, Qiufang Zhang, Tian Qiu, Lei Wang, Guoliang Huang, Jie Qiao, Jundong Wang, and Jing Cheng, Integration of Sperm Motility and chemotaxis Screening with a Microchannel-Based Device,Clinical Chemistry, V56, 1270–1278, 2010。(SCI, IF6.2)

13.Jiang Zhu, Ying Lu, Cheng Deng, Guoliang Huang(通讯作者), Shengyi Chen,Shukuan Xu, Yi Lv, Keith Mitche lson, and Jing Cheng,Assessment of Fluorescence Resonance Energy Transfer for Two-Color DNA Microarray Platforms,Analytical Chemistry, V82, 5304–5312,2010。(SCI, IF5.2)

14.Chao Han, Qiufang Zhang, Rui Ma, Lan Xie, Tian Qiu, Lei Wang, Keith Mitchelson,Jundong Wang, Guoliang Huang(通讯作者), Jie Qiao and Jing Cheng,Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device, Lab on a Chip, V20, p2848-2854, 2010。(SCI, IF6.3)

15.Jiang Zhu, Cheng Deng, Guoliang Huang(通讯作者), Shukuan Xu, Keith Mitchelson, and Jing Cheng,Quantitative Fluorescence Correction Incorporating Forster Resonance Energy Transfer and Its Use for Measurement of Hybridization Efficiency on Microarrays, Analytical Chemistry, V81, N4, 1426-1432, 2009。(SCI, IF5.2)

16.Zhonghua Dong, Guoliang Huang(通讯作者), Shukuan Xu, Cheng Deng, Jiang Zhu, Shengyi Chen, Xiaoyong Yang & Shuying Zhao, Real-time and label-free detection of chloramphenicol residues with specific molecular interaction, Journal of Microscopy, Vol234, p255-261, 2009。(SCI, IF1.9)

17.Guoliang Huang(通讯作者), Cheng Deng, Jiang Zhu, Shukuan Xu, Chao Han, Xiaobo Song, Xiaoyong Yang, Digital imaging scanning system and biomedical applications to biochips, Journal of Biomedical Optics, Vol13, No3, P034006, 2008。(SCI, IF2.9)


联系方式

Email: tshgl at tsinghua.edu.cn

Phone: +86-10-62797213

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